Dextromethorphan is principally a sigma receptor agonist and an SNRI, and dextromethorphan's effects being a dissociative hallucinogen can be attributed partially to dextrorphan (DXO), a metabolite produced when dextromethorphan is metabolized by the body. Both equally dextrorphan and dextromethorphan are NMDA receptor antagonists,[32] alike other

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